Compare/Mixtral 8x22B Instruct vs GPT-5.4 (Non-reasoning)

Mixtral 8x22B InstructvsGPT-5.4 (Non-reasoning)

Side-by-side comparison of pricing, 12 benchmarks, and generation speed.

Mistral

Mixtral 8x22B Instruct

Input
$0/M
Output
$0/M
Speed
TTFT
OpenAI

GPT-5.4 (Non-reasoning)

Input
$2.5/M
Output
$15/M
Speed
62 tok/s
TTFT
0.65s

Winner by Category

Cheaper
Mixtral 8x22B Instruct
Faster (tok/s)
GPT-5.4 (Non-reasoning)
Lower Latency
Mixtral 8x22B Instruct
Benchmarks (3-7)
GPT-5.4 (Non-reasoning)

Pricing Comparison

MetricMixtral 8x22B InstructGPT-5.4 (Non-reasoning)
Input ($/M tokens)$0$2.5
Output ($/M tokens)$0$15
Cost for 1M input + 100K output tokens:
Mixtral 8x22B Instruct$0.00
GPT-5.4 (Non-reasoning)$4.00

Speed Comparison

Output Speed (tokens/s) — higher is better
Mixtral 8x22B Instruct
GPT-5.4 (Non-reasoning)
62 tok/s
Time to First Token (seconds) — lower is better
Mixtral 8x22B Instruct
GPT-5.4 (Non-reasoning)
0.65s

Benchmark Comparison

Data from Artificial Analysis API — 12 benchmarks

Intelligence Index
9.835.4
Coding Index
41.0
Math Index
GPQA Diamond
33.2%74.8%
MMLU-Pro
53.7%
LiveCodeBench
14.8%
AIME 2025
MATH-500
54.5%
Humanity's Last Exam
4.1%10.6%
SciCode
18.8%47.1%
IFBench
48.4%
TerminalBench
37.9%
Mixtral 8x22B Instruct3 wins
7 winsGPT-5.4 (Non-reasoning)

Frequently Asked Questions

Which is cheaper, Mixtral 8x22B Instruct or GPT-5.4 (Non-reasoning)?

Mixtral 8x22B Instruct is cheaper overall. Its blended price (3:1 input/output ratio) is $0.00/M tokens vs $5.63/M for GPT-5.4 (Non-reasoning).

Which model performs better on benchmarks?

GPT-5.4 (Non-reasoning) wins 7 out of 12 benchmarks compared to 3 for Mixtral 8x22B Instruct. See the detailed benchmark chart above for per-category results.

Which is faster for real-time applications?

GPT-5.4 (Non-reasoning) generates tokens faster at 62 tok/s vs 0 tok/s. Mixtral 8x22B Instruct also has lower time-to-first-token (0.00s vs 0.65s).

When should I use Mixtral 8x22B Instruct vs GPT-5.4 (Non-reasoning)?

Choose based on your priorities: Mixtral 8x22B Instruct for lower cost, GPT-5.4 (Non-reasoning) for stronger benchmark performance, and GPT-5.4 (Non-reasoning) for faster generation. For latency-sensitive apps, check the TTFT comparison above.